Xigduo XR is type-2 diabetes medication that combines metformin HCI with the SGLT2 inhibitor. The combination therapy was FDA-approved to help diabetic patients improve glycemic control.
However, the federal agency has since warned that sodium-glucose cotransporter-2 (SGLT2) inhibitors have caused multiple cases of diabetic ketoacidosis, ketoacidosis, or ketosis.
According to the U.S. Food and Drug Administration, between March 2013 and June 2014 type-2 diabetes patients reported that SGLT2 inhibitors caused 20 cases of ketoacidosis, ketoacidosis, or ketosis. The agency further states it received more adverse event reports regarding a link between SGLT2 inhibitors and ketoacidosis since June 2014.
Ketoacidosis is a serious medical condition in which the body produces high levels of ketones (blood acids). Ketones can accumulate in the body when insulin levels are too low or during periods of prolonged fasting.
The FDA warns patients taking SGLT2 inhibitors should watch for signs of ketoacidosis and get medical help immediately if they notice any of the following symptoms:
- Unusual fatigue and sleepiness
- Abdominal pain
- Nausea
- Confusion
- Vomiting
- Difficulty breathing
According to the federal agency, physicians should confirm whether a patient shows signs of ketoacidosis and encourage their patient to discontinue taking an SGLT2 inhibitor if acidosis is confirmed.
The FDA reports that other possible side effects of SGLT2 inhibitors include kidney complications, dehydration and low blood sugar. When combined with other medications, SGLT2 inhibitor side effects have been known to increase cholesterol levels and cause yeast infections.
What Are SGLT2 Inhibitors?
Sodium-glucose cotransporter-2 inhibitors are a class of drugs that effectively treats type-2 diabetes by causing the kidneys to remove sugar from the body and secreting it into the urine. Manufacturers claim that when combined with diet and exercise, SGLT2 inhibitors are an efficient treatment of type-2 diabetes.
In addition to Xigduo XR (dapagliflozin and metformin extended-release), other SGLT2 inhibitors are marketed under the following names:
- Jardiance (empagliflozin)
- Invokana (canagliflozin)
- Farxiga (dapagliflozin)
- Invokamet (canagliflozin and metformin)
- Glyxambi (empagliflozin and linagliptin)
Diabetes Medication Class Action Lawsuit Investigation
Personal injury attorneys have launched a diabetes medication class action lawsuit investigation. If you have suffered from SGLT2 inhibitor side effects including ketoacidosis, ketosis or renal failure, filing a diabetes medication lawsuit may help you receive financial compensation.
A diabetes medication lawsuit may be able to help patients pay medical bills as well as rehabilitation costs and lost wages. Contact a personal injury attorney for a free review to find out if you have legal claim.
In general, diabetes medication lawsuits are filed individually by each plaintiff and are not class actions.
Do YOU have a legal claim? Fill out the form on this page now for a free, immediate, and confidential case evaluation. The attorneys who work with Top Class Actions will contact you if you qualify to let you know if an individual lawsuit or class action lawsuit is best for you. Hurry — statutes of limitations may apply.
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Join a Free Diabetes Medication Class Action Lawsuit Investigation
If you or a loved one suffered ketoacidosis or kidney failure after taking Invokana, Invokamet, Farxiga, Xigduo XR, Jardiance or Glyxambi, you may have a legal claim. See if you qualify to pursue compensation and join a free diabetes medication class action lawsuit investigation by submitting your information for a free case evaluation.
An attorney will contact you if you qualify to discuss the details of your potential case.
- First Name*
- Last Name*
- Street Address*
- Apt. #
- City*
- State*
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- Zip Code*
- Phone*
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- Please select the diabetes medication(s) you have taken:*
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Invokana (canagliflozin)
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Invokamet (canagliflozin and metformin)
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Farxiga (dapagliflozin)
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Xigduo XR (dapagliflozin and metformin extended-release)
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Jardiance (empaglifloziin)
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Glyxambi (empagliflozin and linagliptin)
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- When did you take the diabetes medication(s)?*
- Please select the symptoms you or your loved one were medically diagnosed with:*
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Ketoacidosis
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Kidney Failure
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Myocardial Infarction (Heart Attack)
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Bone fracture(s)
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Not Listed (please detail the symptoms in the comments section if this is selected)
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No diagnosis/injury
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- Please enter any additional details you would like the staff reviewing your submission to know.*
- I understand and agree that submitting this form does not create an attorney-client relationship and that the information I submit is not confidential or privileged and may be shared.*
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Yes
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